1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Employed in the treatment of multiple myeloma. Its synthesis or study is crucial for making sure the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A important compound during the synthesis of imatinib, a drug that targets distinct kinds of most cancers, which includes Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers such as breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is crucial for optimizing the creation system and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilised to take care of breast cancer, and these intermediates are involved with its generation.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the treatment of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis Androsta-5 of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the treatment method of colorectal most cancers and compact mobile lung cancer.
three-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, which have numerous purposes, such as antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This CAS NO. 136572-09-3 compound is involved in the synthesis of various gluconic acid derivatives, which can be Utilized in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication utilized to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).